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diagnosis management oncology rheumatology neurology photo rash algorithm hepatology neck poikiloderma workup adhesivecapsulitis agglutinin anemia antibodies antinuclear apml bandemia behcet
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
) ANA or Anti-NucIear ... context of other symptoms ... likely it will be clinically ... Lymphoproliferative Disorders ... #diagnosis #differential
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Agglutinin Syndrome ... Viral Infection Clinical ... - most common presentation ... younger pts) Differential ... hemolytic #anemia #hematology
Secondary Syphilis Rash Secondary syphilis is the most contagious of all the stages of this disease, and
stages of this disease ... commonly characterize ... The signs and symptoms ... Rash #Diagnosis #Clinical ... #Photo #Dermatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Hemostasis - Differential ... von Willebrand syndrome ... defects in the common ... Bruising #Hemostasis #Differential ... #Diagnosis #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... infection risk secondary ... to 8 years Clinical ... : • Nephrotic syndrome ... hypogammaglobulinemia #immunology #hematology
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
symptoms/signs ... urgent referral to secondary ... presence of metabolic syndrome ... or referral to secondary ... Liver #Enzymes #Differential
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Female:Male 9:1 • Common ... 65 years PBC Pathophysiology ... failure PBC Signs ... and Symptoms: ... patients • +ANA
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
cooled from the normal ... Cryofibrinogenemia Symptoms ... cryoglobulinemia Associated Disorders ... Antiphospholipid syndrome ... #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... initiation • Differential ... diagnosis #management #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
: < 1% Clinically ... or "S" shaped nuclei ... • Autoimmune diseases ... neutrophil #WBC #CBC #hematology ... #pathophysiology
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