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diagnosis dermatology rheumatology alopecia hairloss ana antinuclear pulmonary autoimmune disorders focal hair hypertension loss lymphomas lymphoproliferative management myopathy myositis nonhodgkin
ANA Patterns and Associated Rheumatic Diseases: • Homogeneous: Systemic lupus erythematosus (SLE), Mixed connective tissue disease
ANA Patterns and ... • Nucleolar: Diffuse ... #Antinuclear #Antibodies ... #ANA #patterns ... #differential
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
serial dilution, a pattern ... significant • Pattern ... : The ANA patterns ... not specific ANA Patterns ... #ANA #patterns
Hair Loss (Alopecia) - General (Diffuse and Focal) Differential Diagnosis Algorithm DIFFUSE Scarring - Irreversible-biopsy required • Lupus
and Focal) Differential ... Diagnosis Algorithm ... planopilaris Pattern ... #Differential # ... #causes
Lymphomas and Lymphoproliferative Disorders - Differential Diagnosis Algorithm Hodgkin Lymphoma ~40% - Characteristic For Reed-Sternberg (RS) Cells
Diagnosis Algorithm ... lymphadenopathy more diffuse ... involvement, irregular pattern ... Lymphoproliferative #Disorders #Classification ... pathophysiology #Hematology
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
Focal Hair Loss Pattern ... Hair Loss Pattern ... Alopecia: - Pattern ... alopecia in men (male pattern ... loss), Female pattern
Diffuse Hair Loss (Alopecia) - Differential Diagnosis Algorithm Scarring - Irreversible-biopsy required • Lupus erythematosus • Lichen
Diffuse Hair Loss ... (Alopecia) - Differential ... Diagnosis Algorithm ... planopilaris Pattern ... #causes
Papulosquamous Skin Rash - Differential Diagnosis Algorithm Erythrematous or violaceous papules & plaques with overlying scale •
Diagnosis Algorithm ... Christmas tree pattern ... #Differential # ... Diagnosis #Algorithm ... #causes
Clinical Classification of Pulmonary Hypertension 1. Pulmonary arterial hypertension from pulmonary vasculopathy Idiopathic pulmonary arterial hypertension Heritable gene mutations
Clinical Classification ... and obstructive pattern ... multifactorial mechanisms Hematologic ... #Diagnosis #Differential ... #Causes
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA) • Auto-antibodies ... Goodpasture's cause ... capillaritis leading to diffuse ... hemorrhage (DAH) • Diffuse ... • IF staining patterns
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
tract, and often causes ... - (C-ANCA) pattern ... : antibodies directed ... - (P-ANCA) pattern ... #classification
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