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oncology management algorithm anemia classification hemolytic hodgkins agglutinin autoimmune bruising cancer cold common comparison cryofibrinogenemia cvid dermatologic disorders dyspnea eosinophilia
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
→ Refer to hematology ... Metastatic cancer, Lymphoma ... , Vasculitides, ... IBD, Celiac disease ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... #Diagnosis #hematology ... #rheumatology # ... #nonpalpable #dermatology
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
HTN - Vasculitis ... Hepatopulmonary syndrome ... Transverse myelitis • Hematology ... Deconditioning - Pain ... #diagnosis #causes
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... Alcohol-induced pain ... : Pain in involved ... Hepatosplenomegaly, cytopenias(bleeding ... hematology
Causes of Eosinophilia - Differential Diagnosis Bugs: - Fungus (aspergillosis) - Viral (HIV) - Ectoparasites (scabies, myiasis)
Asthma Tugs (vasculitis ... Primary: - CML - Lymphomas ... Hypereosinophilic Syndrome ... #Diagnosis #Causes ... #hematology
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Diagnosis: Vasculitis ... Polyangiitis #GPA #dermatology ... #rheumatology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... e.g. lupus, CLL, lymphoma ... #differential # ... diagnosis #hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... hepatitis • Lymphoma ... • Nodules • Lymphoid ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... , bleeding, infections ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential ... tract, and often causes ... to exclude are infections ... differential #diagnosis ... #rheumatology #
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