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management oncology agglutinin classification cold cryofibrinogenemia cvid dermatologic erythematosus gap globulin gpa granulomatosis hemolytic hodgkins hypogammaglobulinemia immunodeficiency immunology infectiousdiseases leukemia
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
GPA causes disease ... Rarely dominate the clinical ... Diagnosis: Vasculitis ... Polyangiitis #GPA #dermatology ... #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Nodules • Lymphoid ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Cold Agglutinin Syndrome ... symptoms - most common ... chills, flank pain ... #hematology #diagnosis
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
extramedullary disease ... , bleeding, infections ... - infiltrates (anemia ... #Leukemia #Hematology ... #Oncology #Diagnosis
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... with leukopenia, anemia ... #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... • Most common ... Lung Abscess - Clinical ... Differential Diagnosis ... #pulmonary #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... - Clinical Presentation ... • Pain in LN ... number of sites of disease ... #hematology #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
fibromyalgia) • Infections ... Arthritis: • Joint pain ... common • Antihistone ... Chronic B-cell activation ... #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
malignancies, vasculitis ... Malignancy • Infections ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
by bleeding (petechiae ... Most common cytopenia ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology
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