9 results
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
- Monoclonal - Lymphoid ... symptoms - most common ... younger pts) Differential ... chills, flank pain ... #anemia #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
: Pain in involved ... translocation • Types: Classification ... NonHodgkins #comparison #oncology ... #diagnosis #differential ... #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
: • Most common ... weeks without infection ... aplasia • ITP ... #workup #oncology ... #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Induce blast cell ... initiation • Differential ... Diagnosis: Infection ... #diagnosis #management ... #hematology #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Complications: 1) Infection ... lymphoma (Richter ... chemotherapy for low-risk disease ... #hematology #hemeonc ... #diagnosis #management
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... • Pain in LN ... #diagnosis #classification ... #hematology #oncology ... #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Most common cytopenia ... • Aplastic Anemia ... Myeloproliferative Disease ... blood count with differential ... #hematology #oncology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... fibromyalgia) • Infections ... Arthritis: • Joint pain ... common • Antihistone ... #Rheumatology