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anemia blood reactions activation classification cold hodgkins lymphoma macrophage mas platelets syndrome testing thrombocytosis transfusion transfusions workup
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Cryoglobulins (Vasculitic ... Diagnosis: • hemolytic ... chills, flank pain ... #disease #hemolytic ... #anemia #hematology
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Diagnosis Algorithm ... cardiac valve, vasculitis ... inclusions - If infection ... #Diagnosis #Algorithm ... #workup #hematology
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
Diagnosis Algorithm ... → Refer to hematology ... , Vasculitides, ... #Diagnosis #Algorithm ... #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
: Fever, flank pain ... coagulopathy & ↑bleeding ... • Infection - ... #Transfusions #diagnosis ... #management #hematology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
: Fever, flank pain ... coagulopathy & ↑bleeding ... Infection - Infection ... #Transfusion #diagnosis ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
purpura to mucosal bleeding ... SLE], AOSD) • Infection ... Fibrin degradation products ... #Management #Hematology ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
History of EBV infection ... anemia • Pain ... genes and gene products ... classification #hematology ... #oncology #management
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