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management syndrome pulmonary apml autoimmune cancer classification differentiation emergencies erythematosus hepatology hepatopulmonary hodgkins leukostasis lupus lymphoma lysis mds myelodysplasia myelodysplastic
Dyspnea - Differential Diagnosis Framework Cardiovascular Causes of Dyspnea: • Myocardium: - Heart failure - CAD/ACS - Valvulopathy • Electrical: -
Dyspnea - Differential ... - Too slow • Pericardium ... • Pleura: - Effusion ... Transverse myelitis • Hematology ... #diagnosis #causes
Oncologic Emergencies - Differential Diagnosis Framework HEMATOLOGIC ONCOLOGIC EMERGENCIES: Hyperviscosity Syndrome: • Spontaneous bleeding • Shortness of breath
- Differential ... Diagnosis Framework ... HEMATOLOGIC ... wall) Malignant Pericardial ... Effusion: • Dyspnea
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... high WBC count cause ... Pulm: Hypoxia, dyspnea ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Pathophysiology ... HoTN, edema and effusions ... : >3 symptoms, or ... #management #hematology ... #oncology
Hepatopulmonary Syndrome - Diagnosis and Management Summary A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... lung disease Caused ... left heart 3-6 cardiac ... resolution of symptoms ... #treatment #hepatology
Pulmonary Renal Syndromes - OnePager Summary Autoimmune ANCA vasculitis (AAV): GPA (granulomatous with polyangiitis), EGPA (eosinophilic granulomatosis
EGPA (↓ LVEF, pericardial ... effusion) • PFTs ... or serologies + symptoms ... Goodpasture's cause ... #treatment
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... age 70 years Symptoms ... blood count with differential ... #diagnosis #hematology ... #oncology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Lungs: • Pleural effusions ... Serositis: • Pleural/pericardial ... Induced Lupus: • Symptoms ... #Rheumatology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Cough • Dyspnea ... ingestion • B symptoms ... Hodgkin Lymphoma Treatment ... classification #hematology ... #oncology #management
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
Autoimmune Myositis - Differential ... • Pericarditis/Pericardial ... statins - probably caused ... weakness • Severe cardiac ... Myositis #Myopathy #rheumatology
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