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diagnosis differential management arthritis cll joint lymphocytic msk pain workup algorithm anemia aplastic approach classification diffuse erythematosus hemeonc lad lupus
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Age > 50 • Chronic ... Lymphocytic Leukemia ... Diagnosis #Algorithm #Causes ... #Hematology #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blasts in the peripheral ... Chronic leukemia ... -> AML: Blast crises ... maturation • (Peripheral ... #Hematology #Oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... cytometry • Peripheral ... #CLL #Chronic ... diagnosis #workup #oncology ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... Diagnosis: • Peripheral ... characteristic • Peripheral ... uw_IMresidency #CLL #Chronic ... #oncology #hematology
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Distribution - peripheral ... weeks) Can Be Caused ... arthritis • SLE ... Symmetrical: • RA • SLE ... Diagnosis #MSK #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Non-autoimmune rheumatologic ... Mononeuritis Multiplex • Peripheral ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia ... Erythematosus #Diagnosis #Rheumatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
and petechiae Causes ... virus (EBV) • Leukemia ... anemia) Labs: • Peripheral ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
overlaps with RA, SLE ... ab • RF • Antinuclear ... Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... Sjogrens #Syndrome #Rheumatology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology ... #oncology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
rheumatic fever • Chronic ... syphilis, alcohol - peripheral ... Like in this case ... = RA, SLE, psoriatic ... Joint #Pain #MSK #rheumatology
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