22 results
Fat Embolism Syndrome
Trauma to the long bone or pelvis accounts for —9096 of cases. The diagnosis
Fat Embolism Syndrome ... Pathophysiology ... Embolism of marrow ... Syndrome #Diagnosis ... #Signs #Symptoms
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... hyperviscosity syndrome ... WBC >100k, + lab signs ... rasburicase Tumor Lysis Syndrome ... #Tumor #Lysis #Syndrome
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation Syndrome ... Periodic fever syndromes ... hypersensitivity syndromes ... Macrophage #Activation #Syndrome ... #Diagnosis #Management
Management of Serotonin Syndrome
Identify and stop all serotoninergic medications
 • Avoid inadvertent Rx of serotoninergic meds
Syndrome Identify ... normalize vital signs ... then 2 mg q2h if symptoms ... ucsdim #Serotonin #Syndrome ... #Management #treatment
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... musculoskeletal symptoms ... Psychiatric symptoms ... • Petechiae, purpura ... vasculitis Treatment
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome ... occlusion, Budd-Chiari syndrome ... tests in Behcet syndrome ... adenopathy (PFAPA) syndrome ... #signs #symptoms
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... bleeding, and petechiae ... Constitutional Syndromes ... marrow-failure syndromes ... myelodysplastic syndrome
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
post-sarcoidosis fatigue syndrome ... Specific sarcoidosis syndromes ... ) • Löfgren syndrome ... • Heerfordt syndrome ... #Signs #Symptoms
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Signs and symptoms ... Multiple Sclerosis Treatment ... sclerosis #diagnosis #management ... #neurology #treatment
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Pathophysiology ... Diagnosis: >3 symptoms ... Differentiation #Syndrome ... APML #diagnosis #management