25 results
Petechiae / Purpura - Differential Algorithm by Pathophysiology

Dr. Zaven Sargsyan @sargsyanz

#Petechiae #Purpura #Differential #Algorithm #Pathophysiology #diagnosis
Petechiae / Purpura ... @sargsyanz #Petechiae ... #Purpura #Differential ... #Algorithm #Pathophysiology ... #diagnosis #dermatology
Approach to the Rash in a an oncology patient - MINT-C Mnemonic
M - Malignancy: Leukemia cutis,
the Rash in a an oncology ... Dermatoses: Sweet Syndrome ... Coagulopathy: Purpura ... Thrombocytopenia (ie petechiae ... MINTC #Mnemonic #dermatology
Petechiae/Purpura - Diagnostic Algorithm. Pathophysiology: 1) Represent the passage of erythrocytes from the intravascular to extravascular
Petechiae/Purpura ... Pathophysiology: ... #Diagnosis #Dermatology ... #Rash #Petechiae ... #Purpura #Palpable
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Skin Findings: • Petechiae ... , Palpable purpura ... sensation or pain: • Petechiae ... • Palpable purpura ... • Goodpasture syndrome
Vasculitis Involving the Skin - Differential Diagnosis Framework

Primary: 50% Cutaneous Vasculitis: Leukocytoclastic Vasculitis
Secondary: CTD: SLE, RA
Small Vessel: Petechiae ... , Palpable purpura ... Disease • Cogan syndrome ... Vasculitis #skin #dermatology ... #rheumatology #
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
easy bruising to purpura ... mucosal bleeding (Petechial ... or purpuric rash ... Diagnosis #Management #Hematology ... #Rheumatology
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
musculoskeletal symptoms ... Psychiatric symptoms ... cramping Skin: • Petechia ... • Petechiae, purpura ... #AscorbicAcid #Pathophysiology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... Dehydration • Symptoms ... changes, stroke symptoms ... : • Pathophysiology ... diagnosis #management #hematology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Constitutional Syndromes ... bleeding, and petechiae ... • Improve the symptoms ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Diagnosis: >3 symptoms ... diagnosis #management #hematology ... #oncology