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diagnosis management hematology adultonset differential oncology treatment activation adult arthropathies arthropathy causes chronic cll dermatology erythematosus joint leukemia lupus lymphocytic
Adult-Onset Still's Disease (AOSD) Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Disease (AOSD) ... Rare inflammatory disorder ... maculopapular rash ... #Disease #AOSD ... #rheumatology #diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Diagnosis Algorithm ... Vasculitis - Collagen disorders ... deficiency Work ... cryoglobulins • Skin ... #Petechiae #Rash
Adult-Onset Still's Disease Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia + Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Adult-Onset Still's ... Arthralgia/arthritis, Skin ... rash ± odynophagia ... solid cancers • Systemic ... management #treatment #rheumatology
Joint Disorders - Differential Diagnosis Algorithm Monoarthritis • Septic • Crystalline - Gout
Joint Disorders ... Differential Diagnosis Algorithm ... arthritis - with the skin ... like “butterfly rash ... Differential #Diagnosis #Algorithm
Adult Onset Still's Disease Systemic inflammation with urticarial rash. Rash: • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... Disease Systemic ... maculopapular skin ... #disease #AOSD ... #diagnosis #rheumatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Adult-onset Still ... disease • Systemic ... or purpuric rash ... erythematosus [SLE], AOSD ... #Rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... 3rd Decade Skin ... arthritis, adult-onset Still ... Non-autoimmune rheumatologic ... Seizures • Strokes Skin
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
rendering the immune system ... Hepatomegaly • Skin ... cells can indicate disease ... lymphoproliferative disorders ... Leukemia #diagnosis #workup
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... formed or don’t work ... just beneath the skin ... caused by bleeding (petechiae ... Myeloproliferative Disease
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