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diagnosis rheumatology sle systemic activation comparison disease druginduced laboratory macrophage rheumatic rheumatoid signs symptoms syndrome table testing workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Suspect: Clinical ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... NPSLE): • May involve ... lymphopenia, low PLT • Anemia
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Photosensitivity, Butterfly rash ... of hip (rare), Arthritis ... ) Blood (75%): Anemia ... SLE #systemic #erythematosus
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
erythematosus ... Petechial or purpuric rash ... with leukopenia, anemia ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Constitutional symptoms, Arthritis ... NPSLE rare, Malar rash ... Erythematosus ( ... 40, F:M 9:1 • Clinical
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... erythematosus ( ... the presence of anemia ... ANA and RF (if clinical
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