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diagnosis differential nephrology management treatment high rhabdomyolysis binder binders binding cardiology comparison ddi drugdrug herbal interactions k kbinder medications patiromer
Veltassa (Patiromer) MECHANISM: Potassium Binder INDICATION: Treatment of Hyperkalemia FORMULATION: Powder for oral suspension DOSING: 8.4
oral suspension DOSING ... from other oral drugs ... patients with CKD ... ACE inhibitors, etc ... #Pharmacology
Potassium-Binding Agents to Treat Hyperkalemia Sodium zirconium cyclosilicate (Lokelma): • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... and sodium • Dosing ... of aspiration #Potassium ... #medications #pharmacology ... #table #comparison
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... : • CKD • Poorly ... reactions Common Drugs ... Beta blockers • Antibiotics ... differential #diagnosis #causes
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Clenching of fist during ... : • CKD • Poorly ... reactions Common Drugs ... Beta blockers • Antibiotics ... differential #diagnosis #causes
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Management Summary Causes ... - Toxins - Drugs ... Herpes, Coxsackie, etc ... Monitor potassium ... per day until stable
Rhabdomyolysis - Differential Diagnosis and Management Summary Trauma: • Immobilization, Crush iniury, Compartment syndrome, Electrical injury Exertional: •
Drugs (Statins), ... Herpes, Coxsackie etc ... Monitor potassium ... Dialysis for severe hyperkalemia ... Management #Summary #causes
Hyperkalemia - Diagnosis and Management - GrepMed Handbook S/Sx: Most pts asymptomatic. Weakness, cramping, nausea, paresthesias, palpitations,
NSAIDs, β-blockers, Antibiotics ... VBG (acidosis), CK ... only if no clear cause ... Elimination (see Table ... Management #Treatment #potassium
Clinically Significant Cardiovascular Drug-Drug Interactions With OTC Supplements and Herbal Products Angiotensin-Converting Enzyme Inhibitors (ACEIs) • Night-blooming
Interactions With OTC ... vera, Licorice - Causes ... hypokalemia, increasing ... supplementals #herbal #pharmacology ... #DDI #table #cardiology
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