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Antiplatelet Drugs and their Actions

- Amy Chung, MD, MSc
@AmyChung

#Antiplatelet #Medications #Pharmacology #Pathophysiology #Drugs #Agents #COX #GIIbIIIa
Antiplatelet Drugs ... @AmyChung #Antiplatelet ... #Medications #Pharmacology ... #Pathophysiology ... #Drugs #Agents
The 8 A’s — drugs that interact with warfarin
Antibiotics 
 - Most agents, but especially co-trimoxazole,
The 8 A’s — drugs ... inhibitors) Antiplatelet ... Gingko biloba, dong ... Warfarin #Coumadin #Drug ... Mnemonic #8As #Pharmacology
Mechanisms of Drug-Induced Hyperkalemia 
 • Direct renin inhibitor (Aliskiren)
 • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
Antiplatelet Conversion - Switching Between Oral P2Y12 Inhibitors
A, Switching between oral agents in the acute/early phase.
Antiplatelet Conversion ... Switching between oral agents ... dose of a given drug ... the timing and dosing ... ticagrelor #prasugrel #pharmacology
While certain drugs are used to control seizures, others can induce seizures in patients without a
when multiple agents ... /or preventive dosing ... antiepileptic agents ... #Pharmacology #Lower ... Seizures #Threshold #Differential
Classification of Jaundice
Unconjugated hyperbilirubinemia (predominantly indirect bilirubin)
 • Increased bilirubin production (eg, hemolytic anemias, hemolytic reactions,
Crigler-Najjar syndrome, drug ... or mutation in genes ... coding for bile ... Classification #diagnosis ... #unconjugated #differential
Posterior Reversible Encephalopathy Syndrome (PRES) Overview

Clinico-Radiological Syndrome, characterized by:
 • Headache
 • Seizures
 • Altered mental
Immunosuppressive agents ... Etiology: • Pathophysiology ... Reversible course Differential ... abnormality, Medication/Drug ... titratable parenteral agents
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Acromegaly: frontal bossing ... malignancy Pathophysiology ... Differential Diagnosis ... pachydermoperiostosis, drugs ... Endocrinology #Treatment #Pathophysiology
Medications Contributing to Dysgeusia

Antimicrobial medicines	Macrolides, fluoroquinolones, ampicillin, metronidazole, tetracycline, trimethoprim-sulfamethoxazole, amphotericin B, terbinafine and other antimycotic
other antimycotic drugs ... Chemotherapeutic agents ... Dysgeusia #Induced #Drugs ... #Causes #Differential ... #Diagnosis #Pharmacology