17 results
oncology rheumatology chronic hemophagocytic leukemia lymphocytic lymphohistiocytosis syndrome acquired acromegaly algorithm anemia arterial biliary cholangitis cirrhosis classification common compared comparison
Hemophagocytic Lymphohistiocytosis (HLH) Treatment Primary HLH: - HLH-94 Protocol • Dexamethasone
with infection or autoimmune ... disease, treatment ... for refractory disease ... #Treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
) Pathophysiology ... lymphoma, B-cell ... lymphoma (DLBCL ... solid cancers • Autoimmune ... #management #treatment
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... ) (e.g. lupus, CLL ... , lymphoma, idiopathic ... #differential # ... diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... cells can indicate disease ... microglobulin Treatment ... #workup #oncology ... #hematology
Acquired von Willebrand Syndrome - Diagnosis and Management • Autoantibodies to vWF: Lymphoproliferative disorders (e.g. lymphoma,
disorders (e.g. lymphoma ... thrombocythemia), Autoimmune ... disease • vWF ... #Management #treatment ... #hematology #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Workup: • Full ... number of sites of disease ... Treatment • Early ... #hematology #oncology ... #management
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Lymphocytic Leukemia (CLL ... lymphoma (Richter ... chemotherapy for low-risk disease ... Leukemia #oncology #hematology ... #management
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to impaired B-cell ... • Nodules • Lymphoid ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Hypocomplementemia • Can cause ... Nephrogenic DI Hematologic ... • B cell lymphoma ... Adenocarcinoma Treatment ... #Diagnosis #Management
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... intralobular bile ducts causes ... Examination: • Skin ... Endocrinopathy, Lymphoma ... #workup #hepatology
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