14 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... pseudotumor 4 phenotypes ... biliary, renal, lung ... concentration PET-CT
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
chest (in a V-sign ... auricular papules Clinical ... severity of the disease ... anti-NXP2 Abs Lung ... #dermatology #diagnosis
Problem Representation - Approach to the Infectious Disease Patient

Who: Patient age and host/risk factors (such as
the Infectious Disease ... illness What: Key signs ... that define the clinical ... syndrome - Does ... e.g. brain and lung
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... Chest CT: • Ground-glass ... : • Nephrotic syndrome ... (Epstein-Barr syndrome
Tram Track Sign on Chest CT
 • Parallel, non-tapering airways, extending to the lung periphery.
 •
Tram Track Sign ... ABPA Kartagener's syndrome ... #CT #Lung #Pulmonary ... #diagnosis #radiology ... #clinical
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Lady Windermere Syndrome ... : • Syndrome of ... Lung Disease: ... • Clinical (Symptoms ... Imaging, high res CT
Cushing's Syndrome - Hypercortisolism - Diagnosis and Clinical Features
1) Skin
 • Thin, easily bruisable skin with
Cushing's Syndrome ... Hypercortisolism - Diagnosis ... and Clinical Features ... #Cushings #Syndrome ... #signs #symptoms
Lung Infections in HIV - Differential Diagnosis Framework

Disease by CD4 Count:
Any CD4 Count:
 • Mycobacterium tuberculosis,
- Differential Diagnosis ... Framework Disease ... Pneumonia: • 3 syndromes ... angioinvasive disease ... • CT: Halo sign
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... effusion, Restrictive lung ... Demyelinating syndromes ... erythematosus #signs ... #symptoms #diagnosis
Bronchiectasis - Summary

What?
• Bronchiectasis is derived from the Greek words bronckos meaning airway and ectasis meaning
• Mounier-Kuhn syndrome ... Nasal polyps and signs ... in the adjacent lung ... of the affected lung ... high-resolution chest CT