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hepatology differential injury lfts management transaminitis aflp causes chemistry chronic cirrhosis druginduced failure fatty function gap gastroenterology globulin hepatorenal hrs
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... Injury (DILI) ... #Acute #Chronic ... #Cirrhosis #Hepatology ... gastroenterology #management #diagnosis
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis ... Algorithm DILI ... dechallenge • Acute ... #Diagnosis #Algorithm ... #hepatology
Focused evaluation algorithm for acute liver injury #Liver #Injury #Acute #Evaluation #Algorithm #Diagnosis #Hepatology
Focused evaluation ... algorithm for acute ... Acute #Evaluation ... #Algorithm #Diagnosis ... #Hepatology
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
- Differential Diagnosis ... Hepatopathy • Acute ... Viral Hepatitis ... (>1000): • DILI ... #hepatology #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... - Differential Diagnosis ... Algorithm Vascular ... • Iatrogenic: DILI ... #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Diagnosis Hepatocellular ... , Acute biliary ... #Differential #Diagnosis ... #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
viral hepatitis ... viral hepatitis ... ALF): • Liver ... #chemistry #diagnosis ... #differential #Hepatology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... headache, malaise) → Acute ... 10x ULN), ↑Tbili/Dbili ... : Viral Hepatitis ... #Pregnancy #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
first step in evaluation ... Sarcoidosis) • Liver ... inflammation (acute ... #differential #diagnosis ... #hematology
Hepatorenal Syndrome (HRS) Definition: • Functional, potentially reversible kidney impairment. • Occurs in advanced liver disease: cirrhosis, severe alcoholic
severe alcoholic hepatitis ... , or acute liver ... Diagnosis (Clinical ... transplant evaluation ... Hepatorenal #Syndrome #Hepatology
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