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diagnosis differential macrocytic aafp atlas bloodcell common folicacid hemolytic homocysteine hypogammaglobulinemia immunodeficiency immunology macrocytosis management microcytic microscopy mma morphology nomenclature
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... • Sickle cells ... Consider sickle cell ... Consider RBC membrane disorder ... #workup #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Vitamin B12 or Folate ... McLeod blood group phenotype ... Microangiopathic Hemolytic ... Unstable hemoglobin disorders ... differential #diagnosis #hematology
Algorithm for the evaluation of macrocytic anemia. (RBC = red blood cell; MMA = methylmalonic acid.) Physicians
Algorithm for the ... evaluation of macrocytic ... RBC = red blood cell ... Hemorrhage or hemolysis ... #Workup #AAFP
Anemia Diagnostic Algorithm Mean corpuscular (cell) volume (MCV): Average RBC size. Under 80 = microcytic. Between 80-95
corpuscular (cell ... Red cell distribution ... acute blood loss, hemolysis ... (BM) ablative disorders ... #Workup #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disorder with hypogammaglobulinemia ... to impaired B-cell ... and autoimmune hemolytic ... anemia) • Systemic ... hypogammaglobulinemia #immunology #hematology
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