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diagnosis rheumatology signs systemic approach erythematosus lupus msk pain rheumatoid sle testing vasculitis autoimmune classification disease laboratory myopathy ra rheumatic
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
): • Septic joint ... #rheumatology # ... approach #workup ... #differential # ... diagnosis #arthritis
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
of hip (rare), Arthritis ... in small joints ... Glomerulonephritis Myositis ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
or nerve root Symptoms ... • Inflammatory arthritis ... #Pain #MSK #rheumatology ... #approach #workup ... #differential #
Systemic Sclerosis (Scleroderma) Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs 3
pericarditis • Hepatic ... Musculoskeletal: joint ... acro-osteolysis, myositis ... diagnosis #signs #symptoms ... #testing #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... Diseases • Septic ... of the affected joint ... level to exclude myositis ... #laboratory #workup
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
Vasculitis - Differential ... Presentation: Systemic Symptoms ... vesicular eruption • Joints ... • Progressive symptoms ... Palpable purpura, joint
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis ... - Signs and Symptoms ... nodules, Vascular lesions ... gastritis and peptic ... Musculoskeletal: Joint
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
papulosquamous lesions ... permanent alopecia Differential ... : • Joint pain ... arthropathy • 90% joints ... Induced Lupus: • Symptoms
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... ischemic skin lesions ... vesicular eruption - Joints ... Conjunctivitis, mucositis ... Presentation - Systemic Symptoms
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
- Differential ... Anti-Mi2 (skin lesions ... Syndrome: Fever, joint ... • Nonerosive arthritis ... #differential #
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