14 results
Liver Enzymes (LFTs) - Causes of Hepatocellular and Cholestatic Liver Injury
Hepatocellular Liver Injury
 • AST/ALT elevation
Liver Enzymes (LFTs ... more specific for hepatic ... #LFTs #Hepatocellular ... Transaminitis #diagnosis #differential ... #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Elevated Liver Enzymes ... - Differential ... disease US — Normal ... • Others #LFTs ... #Hepatology #LiverEnzymes
Hemolytic Anemia - Differential Diagnosis Algorithm
 • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia - Differential ... disease (diverse genotypes ... deficiency, Other enzyme ... Diagnosis #Algorithm #workup ... #hematology #testing
Abnormal liver function tests algorithm.
 This figure details the initial response to abnormal liver blood tests.
decision for repeat testing ... #LFTs #Abnormal ... #Algorithm #Hepatology ... #Liver #Enzymes ... #Differential #
Liver Disease in Pregnancy
Intrahepatic Cholestasis of Pregnancy (ICP)
 • Onset/Trimester: 25-32 weeks
 • Typical clinical features:
imaging: Normal ... • Histology: Normal-mild ... Elevated Liver enzymes ... Disease #Pregnancy #hepatology ... hepatitis #comparison #differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... smear, HIV/HCV testing ... gastric bypass), LFT ... #hematology
Algorithm regarding the diagnosis and treatment of Hereditary Hemochromatosis HH. 

Step 1: In the patient with
elevated liver enzymes ... <45% and SF is normal ... elevated, HFE gene testing ... hemochromatosis; HIC, hepatic ... diagnosis #management #hepatology
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... replaced by non-hepatic ... Source of Liver Enzyme ... chemistry #diagnosis #differential ... #Hepatology #transaminitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Proximal limb muscle wasting ... bile ducts Differential ... malignancies, Hepatic ... cholangitis #diagnosis #workup ... #hepatology
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
) Differential ... • Abnormal temperature ... bacteremia • Abnormal ... hypotension or septic ... neutrophil #WBC #CBC #hematology