14 results
IgG4-Related Disease
Clinical history:  Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
 •
IgG4-Related Disease ... Clinical history ... pseudotumor 4 phenotypes ... biliary, renal, lung ... workup #treatment #rheumatology
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
or the anterior chest ... auricular papules Clinical ... severity of the disease ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Clinical features ... underarms, or chest ... involvement Differential ... Lymphomas • Other hematologic ... #hematology
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
Clinical Features ... Purpura, Urticaria Chest ... effusion, Restrictive lung ... pain (20%) Renal disease ... symptoms #diagnosis #rheumatology
Miliary Pattern - Chest Radiology
 • Miliary opacities are scattered, small (1 -4 mm) nodules
 •
Radiology • Miliary ... throughout the lungs ... hematogenous spread of a disease ... #Radiology #differential ... pulmonary #CXR #clinical
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... : Clinical Manifestations ... • Dyspnea, • Chest ... Disease: • Clinical ... NTM #Infections #differential
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Arthritis) - MSK Radiology ... Differential diagnosis ... diffuse chondral disease ... #Radiology #diagnosis ... #msk #rheumatology
On the left a patient who is treated with cytotoxic drugs for a hematologic malignancy.
The radiographic
cytotoxic drugs for a hematologic ... consider drug-related lung ... differential. ... #Clinical #Radiology ... #CTChest #DrugInduced