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diagnosis management dermatology dermatomyositis erythematosus hodgkins lupus lymphoma oncology sle systemic antimda5 antimda5dm antinxp2 antinxp2dm classification common comparison cvid druginduced
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... pseudotumor 4 phenotypes ... biliary, renal, lung ... workup #treatment #rheumatology
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
or the anterior chest ... auricular papules Clinical ... severity of the disease ... anti-NXP2 Abs Lung ... Dermatomyositis #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
• Clinical features ... underarms, or chest ... involvement Differential ... Lymphomas • Other hematologic ... #hematology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Purpura, Urticaria Chest ... effusion, Restrictive lung ... pain (20%) Renal disease ... symptoms #diagnosis #rheumatology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
to 8 years Clinical ... • Chronic lung ... lymphocytic interstitial lung ... Chest CT: • Ground-glass ... hypogammaglobulinemia #immunology #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology
Nontuberculous Mycobacteria (NTM) Infections Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
Hematologic malignancy ... : Clinical Manifestations ... • Dyspnea, • Chest ... Disease: • Clinical ... NTM #Infections #differential
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Serum Copper • Chest ... Immunohistochemical studies (to differentiate ... number of sites of disease ... classification #hematology
On the left a patient who is treated with cytotoxic drugs for a hematologic malignancy. The radiographic
cytotoxic drugs for a hematologic ... consider drug-related lung ... differential. ... #Clinical #Radiology ... #CTChest #DrugInduced
Anti-NXP-2 Dermatomyositis What? DM with generalized subcutaneous edema Pts have more myalgias, more severe weakness, and an increased prevalence
or the anterior chest ... auricular papules Clinical ... had more severe disease ... Non-small-cell lung ... diagnosis #management #rheumatology
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