11 results
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
Summary of dosing ... hypoglycaemic agents #Diabetes ... #Diabetic #Medications ... #Pharmacology # ... Renal #Impairment #CKD
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... Continue ACEi or ... evidence-based pharmacologic ... #Diabetes #CKD # ... #KDIGO #eGFR #Insulin
Estimating the Total Daily Dose (TDD) of Insulin: Weight-Based Dosing
TDD in units of insulin = N
: Weight-Based Dosing ... (stage IV or V CKD ... #dosing #estimation ... Weight #Based #pharmacology ... endocrinology #diabetes
Sulfonylureas - Pharmacology Summary
Mechanisms of Action: Binds to the ATP-sensitive potassium channel in pancreatic beta cells,
Sulfonylureas - Pharmacology ... Summary Mechanisms ... cells, triggering insulin ... contraindicated in CKD ... diabetes #endocrinology
Diabetes Medications Summary Table
Insulin
Lifestyle modifications
Metformin
Sulfonylureas
GLP-1 receptor agonists - ↓ major adverse CV events
TZDs
DPP-4 inhibitors
SGLT2 inhibitors -
Diabetes Medications ... Summary Table ... Insulin Lifestyle ... Improved outcomes in CKD ... table #comparison #management
DPP4 Inhibitors - Normal and Renal Dosing

Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... -> Stimulates Insulin ... will stimulate insulin ... #Pharmacology # ... Management #Diabetes
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... Hyperkalemia: • CKD ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
oral suspension DOSING ... patients with CKD ... , HF, or diabetes ... ACE inhibitors, ... #Hyperkalemia #Pharmacology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
Clenching of fist during ... Hyperkalemia: • CKD ... • NSAIDs • ACE ... (Uncontrolled diabetes ... paralysis - Insulin
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
Summary - GrepMed ... Acromegaly: frontal bossing ... • Metabolic: Insulin ... Mortality due to CVD ... Acromegaloid): insulin