9 results
ANTI-MDA5 DERMATOMYOSITIS

Cutaneous manifestations:
• Periorbital heliotrope (blue-purple) rash with edema
• Erythematous rash on the face, or the
Cutaneous manifestations ... ulcerations • Skin ... ulcerations • Auricular skin ... • Skin vasculopathies ... #rheumatology #
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
malignancy) • Cutaneous ... , hair growth, skin ... tags, skin thickening ... malignancy Pathophysiology ... or refractory cases
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... involvement (2%) Cutaneous ... Treat primary cause ... #treatment #management ... #hematology
Anti-NXP-2 Dermatomyositis

What?
DM with generalized subcutaneous edema
Pts have more myalgias, more severe weakness, and an increased prevalence
in the neck Cutaneous ... have typical DM skin ... Muscle atrophy may cause ... #diagnosis #management ... #rheumatology #
Scurvy (Vitamin C Deficiency) - Diagnosis and Management

Vitamin C is required for hydroxylation of proline residues
Diagnosis and Management ... integrity of: • Skin ... Muscle cramping Skin ... capillaritis, cutaneous ... , or any other cause
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
pulmonary symptoms • Rheumatologic ... osteomyelitis or skin ... Aspergillosis Pathophysiology ... Mouth, throat, skin ... Fungal #Diagnosis #Management
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... include: fever, cutaneous ... infections with skin ... Transfusion #diagnosis #management ... #hematology #reactions
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
Causes purpura & ... include: fever, cutaneous ... infections with skin ... Transfusions #diagnosis #management ... #hematology #reactions
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Lacrimal swelling • Skin ... Hypocomplementemia • Can cause ... ) • Cutaneous vasculitis ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management