18 results
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... purple, hemorrhagic skin ... Kasabach-Merritt syndrome ... Gardner-Diamond syndrome ... #rheumatology #
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA)

Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Polyangiitis (GPA) Skin ... GPA causes disease ... reticularis Differential ... • Goodpasture syndrome ... rash #diagnosis #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
response to local skin ... test (this is a skin ... ) Differential Diagnosis ... #diagnosis #management ... signs #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... tract, and often causes ... • Cogan Syndrome ... Differential ... #diagnosis #rheumatology
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
• Heavy Chain disease ... Alpha & Mu) Skin ... thrombosis+Pulm HTN+skin ... #Monoclonal #Differential ... #Diagnosis #Oncology
Venous Thrombosis vs Arterial Thrombosis - Differential Diagnosis Framework

VENOUS THROMBOSIS

 • Acquired Risk Factors:
	- >48 hours
Myeloproliferative disease ... Testosterone - Coumadin skin ... • Nephrotic Syndrome ... coagulation and other causes ... #differential #
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Headaches • Pale skin ... and petechiae Causes ... Aplastic #Anemia #oncology ... #hematology #diagnosis ... #management
Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS)
Definition: 
 • Severe adverse drug reaction, characterized by
characterized by extensive skin ... Edema in 70% of cases ... Skin involvement ... Resolution > 15 days Differentials ... SinaiBmoreIMRes #DRESS #Syndrome
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... tract, and often causes ... #Vasculitis #Differential ... #Diagnosis #Rheumatology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
just beneath the skin ... Myeloproliferative Disease ... blood count with differential ... #diagnosis #hematology ... #oncology