3 results
Statin Induced Muscle Toxicity - Summary

Clinical Presentation:
 • Elevations of serum creatine kinase with proximal myalgia
weakness without skin ... any time during treatment ... polymyositis, dermatomyositis ... resolve after DC ... Statin Treatment
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
activates JAK-STAT ... Symptoms: • GH deficiency ... tunnel, OSA, Incr skin ... #FeedbackLoop #endocrinology ... #pathophysiology
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... anemia, yellow skin ... palpitations), skin ... malabsorptive state ... Check for IF ab Treatment