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diagnosis symptoms 21ohd complications endocrinology extraarticular genetics lupus manifestations mucocutaneous peds ra rheumatoidarthritis sle
21-Hydroxylase Deficiency (21-OHD): Pathogenesis and Clinical Findings Autosomal recessive mutation in CYP21A2 coding for the enzyme 21-OHase
enzyme 21-OHase causes ... Signs/Symptoms/Complications ... cold & mottled skin ... #21OHD #pathophysiology ... endocrinology #peds #pediatrics
Rheumatoid arthritis (RA): Extra-articular manifestations Skin: • Inflammation of skin (esp. over areas of stress) forms
manifestations Skin ... esp legs) -> Leg Ulcers ... inflammation tends to cause ... RheumatoidArthritis #RA #pathophysiology ... #signs #symptoms
Lupus (SLE): Mucocutaneous Manifestations • Langerhan cells and keratinocytes release cytokines -> localized inflammatory response ->
hair follicles -> causes ... inflammation on skin ... > Mouth, Nasal Ulcers ... Manifestations #pathophysiology ... #diagnosis #signs
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