11 results
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... Behcet disease) Differential ... , AS Treatment: ... inhibitors • Uveitis- Ophthalmology ... management #signs #symptoms
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Fever, Arthralgia/arthritis ... , Skin rash ± odynophagia ... fraction < 20% Differential ... • Ocular: uveitis ... diagnosis #management #treatment
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
Vasculitides - Differential ... ulcers, cutaneous, ocular ... • Cogan Syndrome ... : - Ocular inflammatory ... Presentation - Systemic Symptoms
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... Vasculitis Differential ... Presentation: Systemic Symptoms ... • Progressive symptoms ... : Ocular inflammatory
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Adult Onset Still's ... the chest/trunk Symptoms ... A nonpruritic macular ... maculopapular skin ... Treatment - Mild
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
very remarkable w/differential ... required due to skip ... of the steroid treatment ... Treatment of GCA ... required +/- prompt ophthalmology
The Stages of Syphilis 

Primary Syphilis 
- The chancre lesion is the hallmark of primary syphilis.
Without treatment ... - Ocular syphilis ... exposure to or symptoms ... granuIomas on skin ... aneurysm and coronary arteritis
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
3rd Decade Skin ... Erythematous, macular ... permanent alopecia Differential ... , adult-onset Still ... Induced Lupus: • Symptoms
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
osteomyelitis or skin ... organism into the skin ... osteoarticular, pulmonary, ocular ... Meningitis, septic arthritis ... Mouth, throat, skin
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... cavitating pneumonia, skin ... lesions, ocular ... Zoster flare, ocular ... #Differential #