47 results
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
high WBC count cause ... , dyspnea, +/- CXR ... WBC >100k, + lab signs ... unless worrisome EKG ... #TLS #diagnosis
Pericarditis can be seen on EKG with diffuse ST elevations without reciprocal changes along with diffuse
can be seen on EKG ... First line treatment ... in refractory cases ... #Diagnosis #Signs ... #Symptoms
Syncope is a sudden, transient loss of consciousness, which is thought to be secondary to cerebral
frequently benign causes ... carotid sinus syndrome ... orthostatic vital sign ... Further diagnostics ... The treatment strategy
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
Treatment depends ... maintained fever CAUSES ... hyperthermia crisis (late sign ... amphetamines) Toxic: • Radiologic ... Anesthesia #Checklist #Diagnosis
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
• Or brainstem syndromes ... Multiple Sclerosis Diagnosis ... Signs and symptoms ... Multiple Sclerosis Treatment ... management #neurology #treatment
Sarcoidosis - Diagnosis and Management Summary
Epidemiology
1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
Sarcoidosis - Diagnosis ... at the time of diagnosis ... (e.g. incidental ... CXR finding) ... #Management #Signs
Eosinophil Disorders Testing Algorithm
INDICATIONS FOR TESTING:
 • Peripheral blood eosinophilia/hypereosinophilia uncovered incidentally during medical evaluation or
for secondary causes ... glucocorticoid treatment ... organ-specific signs ... or symptoms (eg ... #Differential #diagnosis
BEE Syndromes - Non-inflammatory Causes

Immune-mediated conditions affecting the Brain, Eye, and Ear

Visual or auditory symptoms in
Non-inflammatory Causes ... Visual or auditory symptoms ... conjunction with symptoms ... and treatment can ... skull neoplasms (e.g
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Prednisone 5mg/kg ... common • Imaging: CXR ... : >3 symptoms, or
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
myasthenia Diagnosis ... Serologic and EMG ... test - Cogan sign ... - Peek sign ... Myasthenia #Gravis #diagnosis