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diagnosis differential clinical video neurology algorithm ophthalmology management msk cardiology nephrology ocular orthopedics pediatrics sign dermatology sports test hematology peds
Type IV Hypersensitivity: Pathogenesis and clinical findings Definition: Unique because it is entirely T-Cell mediated; exposure to
mediated; exposure to allergen ... causes development ... of allergen-specific ... Allergic reaction ... Stevens-Johnson Syndrome
Hypersensitivity: Summary Type I Hypersensitivity: • Immunological Mediator: lgE • Immunological Target: Allergen Molecules • Ex: Antibiotic
Immunological Target: Allergen ... fever, Urticaria, Allergic ... Stevens-Johnson Syndrome ... Hypersensitivity #Allergy ... #Allergic #Reactions
Angioedema - Classification Diagnosis and Treatment Types of Angioedema: • Acute allergic angioedema - Usually occurs with
Angioedema: • Acute allergic ... exposure • Non-allergic ... cell-mediated in > 90% of cases ... or avoiding the allergen ... Treatment #management #allergy
Nail Pathologies - Findings in or Near Nails Paronychia A superficial infection of the proximal and lateral
Local causes include ... infection, and allergic ... Systemic causes ... seen in Reiter's syndrome ... Clinical #Signs #PhysicalExam
Acute Pharyngitis: Differential Diagnosis Infectious: • Respiratory viruses (25-45%) • Group A Strep (5-15%) • Other bacteria:
Acute Retroviral Syndrome ... Diffuse viral syndromes ... Noninfectious: • Allergic ... PFAPA, Behcet syndrome ... Differential #Diagnosis #causes
Marcus Gunn Phenomenon - Jaw Winking Syndrome Jaw-winking syndrome is thought to be caused by abnormal innervation
- Jaw Winking Syndrome ... Jaw-winking syndrome ... thought to be caused ... Most cases are congenital ... video #neurology #physicalexam
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 Causes of Erythema Nodosum - Mnemonic NO cause found in 60% of cases Drugs (antibiotics e.g., sulfonamides, amoxicillin) Oral
Causes of Erythema ... Mnemonic NO cause ... found in 60% of cases ... Sarcoidosis or Lofgren's syndrome ... Nodosum #Mnemonic #Causes
Pemberton's Sign caused by a Retrosternal Thyroid Goiter Elevating the arms causes the previously flat neck veins
Pemberton's Sign caused ... Elevating the arms causes ... superior vena cava syndrome ... Thyroid #Goiter #PhysicalExam ... neck #mass #SVC #Syndrome
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 Eosinophils (Eos) and hypereosinophilia (HE) Caused by eosinophilopoietic cytokines Common causes: - Drug reaction - Helminth infection -
hypereosinophilia (HE) Caused ... cytokines Common causes ... infection - Allergic ... disease Rare causes ... + T cells) - Allergic
Hyperthermic Syndromes - This table summarizes the similarities and differences between some toxicologic causes of hyperthermic
Hyperthermic Syndromes ... some toxicologic causes ... of hyperthermic syndromes ... • Serotonin syndrome ... #Hyperthermic #Syndromes
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