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management differential hematology symptoms vasculitis behcet classification clinical comatose cryofibrinogenemia disease gravis leukostasis lysis manifestations monoclonal myasthenia neuromyelitis nikolskys nmo
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN) Nikolsky's sign is a clinical dermatological sign which is present
Stevens-Johnson Syndrome ... , caused by the ... differentiating between the diagnosis ... #TEN #Dermatology ... #PhysicalExam #
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 Neuromyelitis Optica (NMO) - Clinical Manifestations • Optic neuritis: Reduced visual acuity, ranging from mild to
desaturation, Scotoma, Ocular ... involvement: Intractable nausea ... Manifestations #diagnosis ... #neurology #symptoms ... #signs
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... skin injury) • Neurologic ... ) Differential Diagnosis ... #signs #symptoms ... #rheumatology #
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
vs Tumor Lysis Syndrome ... high WBC count cause ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Myasthenia Gravis Overview Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction. Ab to
Ocular- 50%: Ptosis ... myasthenia Diagnosis ... test - Cogan sign ... - Peek sign ... #management #neurology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rule out other causes ... sites such as the collar ... #Rheumatology # ... diagnosis #management ... #Dermatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
pulmonary emboli, and ocular ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... #rheumatology # ... hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
capillary leak syndrome ... et diutinum Neurologic ... Hypergammaglobulinemic macular ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... tract, and often causes ... • Cogan Syndrome ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... purpura: Strong sign ... affects the skin, neurologic ... tract, and often causes ... #Rheumatology
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