13 results
Leser–Trélat Sign on Physical Exam

Acute onset of multiple seborrheic keratoses, often a paraneoplastic sign of malignancy.

#Leser
Leser–Trélat Sign ... paraneoplastic sign ... #LeserTrelat #Sign ... #PhysicalExam # ... #skin #dermatology
Nikolsky's Sign in Toxic Epidermal Necrolysis (TEN)

Nikolsky's sign is a clinical dermatological sign which is present
Nikolsky's Sign ... Nikolsky's sign ... Nikolsky's sign ... #TEN #Dermatology ... #PhysicalExam #
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
association • M > F Clinical ... syndrome (Clinical ... disease) Differential ... Syndrome #diagnosis #management ... #signs #symptoms
Lymphocutaneous Sporotrichiosis Infection

Landscaper w/ painless nodular rash of arm present for months wax and wane; diagnosis?
Lymphocutaneous
trauma leads to skin ... painless, no systemic signs ... biopsy preferred Differential ... leishmania, Tb, NTM; less ... Sporotrichiosis #Infection #clinical
Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign")

Asboe-Hansen sign is the extension
Asboe-Hansen sign ... or "Nikolsky II sign ... #PhysicalExam # ... Bullae #Blister #Dermatology ... #skin
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Hyperthyroidism Overview Clinical ... Toxic diffuse goiter ... Thickening of skin ... causes #diagnosis #differential ... endocrinology #signs
Common Dermatological Conditions - Distribution and Morphology
 • Acne vulgaris - Face, upper back, chest -
Ankles, lower legs ... associated with signs ... erosions • Herpes zoster ... ; pruritis #dermatology ... #rash #differential
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
weakness, arms > legs ... life-threatening Differential ... test - Cogan sign ... - Peek sign ... Gravis #diagnosis #management
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
Vasculitis - Differential ... purpura: Strong sign ... arthralgia, arm/leg ... purpura (lower legs ... vasculitis • Behcet
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
Transverse Myelitis - Clinical ... • Bilateral signs ... Infections: - Herpes zoster ... Myelitis #diagnosis #management ... #neurology #differential