Asboe-Hansen sign (also known as "indirect Nikolsky sign" or "Nikolsky II sign") Asboe-Hansen sign is the extension of an unruptured blister with the application of pressure. Best-detected by drawing a margin around the bulla prior. Asboe-Hansen sign is a useful clinical tool for diagnosing toxic epidermal necrolysis (TEN). Asboe-Hansen sign can be employed to generate a fresh bulla for lesional skin biopsy in the evaluation of TEN. #AsboeHansen #sign #PhysicalExam #Video #Clinical #Bullae #Blister #Dermatology #skin
