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diagnosis differential symptoms management vasculitis arthritis autoimmune behcet classification cryofibrinogenemia disease erythematosus lupus monoclonal myopathy myositis oncology paraproteinemias ra rheumatoid
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features of Systemic ... defect (rare) Raynaud's ... Demyelinating syndromes ... erythematosus #signs ... symptoms #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Systemic disease ... ulceration • Ocular ... : Giant retinal ... diagnosis #management #signs ... #symptoms #rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
processes: • Systemic ... Arthralgias • Raynaud ... thrombi including retinal ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
clubbing Clarkson/Systemic ... neuropathy) • Systemic ... Hypergammaglobulinemic macular ... vascular beds-renal, retinal ... Paraproteinemias #Hematology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Rheumatoid Arthritis - Signs ... and Symptoms • Ocular ... Rheumatoid vasculitis, Raynaud's ... Thrombocytosis, Felty's syndrome ... Symptoms #diagnosis #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
ulcers, cutaneous, ocular ... • Cogan Syndrome ... : - Ocular inflammatory ... purpura: strong sign ... differential #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Central nervous system ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud ... #Rheumatology #
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
purpura: Strong sign ... ulcers, cutaneous, ocular ... vasculitis • Cogan syndrome ... : Ocular inflammatory ... Differential #Diagnosis #Rheumatology
Autoimmune Myositis - Differential Diagnosis Framework Inflammatory Myopathies: Commonly symmetric proximal muscle weakness, no substantial muscle pain
papules and Gottron sign ... ) • Shawl sign ... joint pain and Raynaud ... • Conduction system ... Myositis #Myopathy #rheumatology
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