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diagnosis classification erythematosus oncology sle systemic behcet cryofibrinogenemia disease hodgkins lymphoma monoclonal paraproteinemias signs sjogrens summary symptoms vasculitides vasculitis
Systemic Lupus Erythematosus - Summary Antinuclear (ANA) - 95% - Initial screening test Anti-dsDNA - 50% • Associated
Systemic Lupus Erythematosus ... Anti-UI-ribonucleoprotein - 35% • Raynaud ... #Systemic #Lupus ... Summary #diagnosis #rheumatology ... #management
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
ulceration • Ocular ... Behcet disease) Differential ... : Giant retinal ... #diagnosis #management ... signs #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Erythematous, macular ... permanent alopecia Differential ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... Erythematosus #Diagnosis #Rheumatology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Hypergammaglobulinemic macular ... to cold IgG • Lupus ... vascular beds-renal, retinal ... Paraproteinemias #Hematology ... #Monoclonal #Differential
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Arthralgias • Raynaud ... thrombi including retinal ... Antiphospholipid syndrome ... Cryofibrinogenemia #diagnosis #rheumatology ... #hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
Vasculitides - Differential ... inflammation Others: • Lupus ... • Cogan Syndrome ... such as systemic lupus ... #diagnosis #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
gland) biopsy • Ocular ... Nephrogenic DI Hematologic ... Cryoglobulinemia (4%-12%), Raynaud ... #Rheumatology # ... Diagnosis #Management
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
subtypes: - Nodular ... in this subtype retain ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management
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