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diagnosis hematology causes algorithm systemic generalized management pruritus rheumatology acromegaly activation agglutinin cold disease elevatedmcv endocrinology hemolysis hemolytic macrocytic macrocytosis
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis - Differential ... Diagnosis Secondary ... malignancies • Anemia ... Myelodysplastic syndrome ... #secondary
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... • Nephrotic syndrome ... NailDisorders #Systemic #Secondary ... #dermatology #Differential
Pruritus - Generalized Differential Diagnosis Algorithm - Systemic and Primary Causes == Primary Skin Lesions == Macules /
Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome ... Pruritus #primary #secondary ... #generalized #dermatology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Volume (MCV) - Differential ... Myelodysplastic Syndromes ... Liver Function Tests ... Liver Function Tests ... Algorithm #Causes #Hematology
Hemolysis - Differential Diagnosis Framework 1) Environment - Fragmentation - MAHA: TTP, HUS, DIC, HELLP
Hemolysis - Differential ... Drug-associated, PCH, Evans Syndrome ... Defects: Sickle cell anemia ... Laboratory Tests ... #Diagnosis #hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
AIHA Primary Secondary ... Cold Agglutinin Syndrome ... younger pts) Differential ... • Diagnostic Test ... Donath-Landsteiner test
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... leakage of RBC's secondary ... - Hemolytic anemia ... Kasabach-Merritt syndrome ... #nonpalpable #dermatology
Pruritus - No Primary Skin Lesion - Differential Diagnosis Algorithm Blood Glucose: • Diabetes Mellitus Liver Function Tests/Enzymes:
Liver Function Tests ... renal failure/uremia ... Myelodisplastic syndrome ... #Pruritus #secondary ... #generalized #dermatology
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... in primary or secondary ... Fecal occult blood test ... Algorithm #Causes #dermatology ... #physicalexam
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Causes • Anemia ... • Aplastic Anemia ... blood count with differential ... #diagnosis #hematology
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