9 results
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
/ Symptoms / Complications ... partial retinal red reflex ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Alzheimer’s Disease: Pathogenesis and Clinical Findings
Risk factor for Late Onset Alzheimer's (99% of cases):
 - Increasing
Alzheimer’s Disease ... / Symptoms / Complications ... seizure, primitive reflexes ... AlzheimersDisease #Dementia #pathophysiology ... #geriatrics #diagnosis
Cauda Equina Syndrome
Causes:
 • Large lumbar degenerative disc herniation (central)
 • Severe lumbar spondylosis
 • Neoplasm
/ Symptoms / Complications ... of normal leg reflexes ... CaudaEquina #Syndrome #MSK ... #pathophysiology ... #diagnosis #symptoms
The Neurological Evaluation of a Comatose Patient

Definition:
 • Coma: a state of unresponsiveness; the absence of
Differential Diagnosis ... • Mutism Pathophysiology ... myoclonic movements, tremors ... • Examine for signs ... caseyalbin #PhysicalExam
Bulimia Nervosa: Signs and Symptoms
Associated Psychological / Behavioural Features
 • Feelings of shame, guilt and embarrassment
erosion and gum disease ... Symptoms related to complications ... inducing vomiting #BulimiaNervosa ... #pathophysiology ... #diagnosis #signs
Meralgia paresthetica: Pathogenesis and Clinical Findings
Compression/injury of Lateral Femoral Cutaneous Nerve (LFCN) -> Meralgia paresthetica
 •
intervertebral disc disease ... gait, strength, reflexes ... MeralgiaParesthetica #MSK ... #pathophysiology ... #signs #symptoms
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Spasticity - Reflexes ... bouts of HTN Diagnostic ... • Bilateral signs ... Enhancement - TM and tumor
Bulimia Nervosa: Complications
GASTROINTESTINAL
 • Dehydration & inability to digest food -> Constipation
 • Recurrent vomiting exposes
Bulimia Nervosa: Complications ... inflammation -> Acid reflux ... Cardiac Arrest #BulimiaNervosa ... #pathophysiology ... #diagnosis #signs
Paget’s Disease: Complications
Abnormal Osteoclasts cause excessive bone turnover -> Incr bone resorption, Incr (abnormal) bone formation

MSK
Paget’s Disease: ... Complications ... bone formation MSK ... PagetsDisease #pathophysiology ... #diagnosis #signs