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hematology activation apml capillary clarksons differentiation disease fungal leak macrophage mas mycoses oncology sjogrens timeline
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Triggers: ATRA treatment ... Imaging: CXR- pulmonary ... : Infection (sepsis ... #management #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
SLE], AOSD) • Infection ... Hypofibrinogenemia • ↑ PT ↑ PTT ... Treatment: • Corticosteroids ... #Diagnosis #Management ... #Hematology #Rheumatology
Clarkson’s Disease - Capillary leak syndrome Epidemiology: Roughly 150 published cases, Median age 50 years, No sex
Capillary leak syndrome ... filling +++ (risk of pulmonary ... of infections) ... #diagnosis #management ... #rheumatology
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... Adenocarcinoma Treatment ... lubricants • Pharmacologic ... #Rheumatology # ... Diagnosis #Management
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
symptoms • Rheumatologic ... Histoplasmosis Diagnosis ... : • Pulmonary ( ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
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