10 results
Top tips for triaging and treating kids with Pitt Hopkins Syndrome
#Diagnosis #Management #PatientInfo #Peds #Pediatrics #PittHopkins
treating kids with Pitt ... Hopkins Syndrome ... #Diagnosis #Management
Treatment Approach to Hodgkin's Lymphoma

By Matthew Ho, MD PhD @MatthewHoMD
With Credit: Dr Sunita Nasta and Dr
guidelines #Hodgkins ... Lymphoma #oncology #Hematology ... #management #treatment
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 ... IFN-y) → Excessive activation ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... complex → plt activation ... Management: • ... diagnosis and management ... #Treatment #Hematology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Macrophage Activation ... Hypofibrinogenemia • ↑ PT ↑ PTT ... MAS #Macrophage #Activation ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Prolonged PT/PTT ... PT/INR: ↑ • PTT ... causes #treatment #management ... #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
excessive macrophage activation ... Lymphohistiocytosis #diagnosis #management ... #treatment #hematology
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Escalated BEACOPP #Hodgkins ... classification #hematology ... #oncology #management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
Malignancy Risk: • Non-Hodgkins ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
Scleroderma Renal Crisis (SRC)

Clinical Presentation of Scleroderma Renal Crisis:
1) Acute kidney injury
2) Abrupt onset of hypertension
3)
endothelial cell activation ... of arteries Management ... Renal #Crisis #rheumatology ... nephrology #diagnosis #management