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differential ascites lfts algorithm causes chemistry cholangitis gradient interpretation laboratory primary rheumatology saag syndrome tests workup activation alkphos astalt coagulation
Diagnosis of ascites according to the serum ascites albumin gradient (SAAG) SAAG ≥ 1.1: - Ascitic protein
Diagnosis of ascites ... protein ≤ 2.5 g/dL: Cirrhosis ... syndrome, Massive liver ... syndrome SAAG < 1.1: Biliary ... #gradient #hepatology
Liver Function Tests (LFTs) - Normal Values and Interpretation Alanine aminotransferase (ALT/SGPT) - Liver, cardiac & skeletal
, biliary epithelium ... Conjugated/DBili) - Biliary ... Crigler-Najjar) Albumin ... Interpretation #diagnosis ... #hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
- Differential Diagnosis ... function: INR, bilirubin ... , albumin Post-Hepatic ... pregnancy • Primary biliary ... #causes #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Phosphatase and Bilirubin ... circulates with albumin ... Released from albumin ... #Hepatology #Pathophysiology ... #Diagnosis #LFTs
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... /Liver failure ... slightly elevated • Bilirubin ... or higher • Liver ... #workup #hepatology
Serum Ascites Albumin Gradient (SAAG) - Differential Diagnosis High albumin gradient (>1.1 g/dl): - Cirrhosis - Alcoholic
- Differential Diagnosis ... >1.1 g/dl): - Cirrhosis ... - Acute fatty liver ... Tuberculosis - Biliary ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential Diagnosis ... Extrahepatic - Biliary ... hepatitis: < 1 • Cirrhosis ... #differential #diagnosis ... #algorithm #hepatology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
brown: elevated bilirubin ... differential, albumin ... chylous ascites), bilirubin ... concentration (bowel or biliary ... #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
week • Direct bilirubin ... Production: • Albumin ... hepatitis: < 1 • Cirrhosis ... #chemistry #diagnosis ... #differential #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
to multi-focal biliary ... asymptomatic at diagnosis ... disease management ... #management #summary ... #Hepatology
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