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diagnosis causes pbc psc alkphos astalt biliary chemistry coagulation comparison dic differential disseminated hypertension intravascular laboratory lfts macrophage mas metabolism
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Biliary Cirrhosis ... Cholangitis ... #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
65 years PBC Pathophysiology ... /Liver failure ... slightly elevated • Bilirubin ... or higher • Liver ... diagnosis #workup #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
Phosphatase and Bilirubin ... CAST) • ALT: primarily ... circulates with albumin ... Released from albumin ... #Hepatology #Pathophysiology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
function: INR, bilirubin ... , albumin Post-Hepatic ... sarcoidosis) • Liver ... pregnancy • Primary ... Diagnosis #causes #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... disease management ... AutoImmuneLiver #PSC #Primary ... #diagnosis #management ... #summary #Hepatology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Macrophage Activation ... thrombocytopenia • Liver ... ↑ AST ↑ ALT ↑ bilirubin ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... DIC • Severe Liver ... Treatment: • Treat primary ... causes #treatment #management ... #hematology
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