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diagnosis differential treatment algorithm causes hbv primary psc biliary chemistry chronic coagulation comparison dic disseminated gap globulin hepatitis hepbv hypertension
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Primary Biliary Cirrhosis ... Primary Sclerosing Cholangitis ... #pathophysiology ... #pbc #psc #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Pathophysiology ... slightly elevated • Bilirubin ... Diagnosis: • Viral hepatitis ... #PBC #cholangitis ... diagnosis #workup #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
, PBC, PSC, IgG4 ... Chronic viral hepatitis ... : < 1 • Cirrhosis ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Check Acute viral hepatitis ... Check Acute viral hepatitis ... Production: • Albumin ... : < 1 • Cirrhosis ... #differential #Hepatology
Portal Hypertension - Differential Diagnosis Portal Pressure = the pressure difference between the pressure in the portal
function: INR, bilirubin ... , albumin Post-Hepatic ... /acute hepatitis ... sarcoidosis) • Liver ... Diagnosis #causes #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
• CHOLANGITIS ... • CIRRHOSIS - ... disease management ... #diagnosis #management ... #summary #Hepatology
Chronic Hepatitis B - Diagnosis and Management Algorithm • Who to treat: Essentially treat the pts with
Diagnosis and Management ... viremia or have cirrhosis ... • Monitor: CBC ... Algorithm #Diagnosis #Management ... #Treatment #Hepatology
Hepatitis B - Treatment Indications Treatment not indicated: • Immune tolerant state - HBe-Ag detectable, high HBV
Hepatitis B - Treatment ... Presence of CP or PC ... injury (INR > 2, bilirubin ... #Indications #management ... #hepatology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
• Prolonged PT/PTT ... protein C and S Pathophysiology ... DIC • Severe Liver ... causes #treatment #management ... #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Sarcoidosis) • Liver ... disease: Cirrhosis ... , PBC, PSC, Viral ... gastric tumors • Hematology ... differential #diagnosis #hematology
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