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Growth Hormone Excess - Pathogenesis and clinical findings
 • Acromegaly and gigantism share the same pathophysiology
clinical findings • Acromegaly ... share the same pathophysiology ... rare causes of acromegaly ... fraction • HTN #GrowthHormone ... endocrinology #pathophysiology
Feedback Loop: Growth Hormone (GH)
Growth Hormone:
 • Liver -> GHR activates JAK-STAT pathway -> Incr IGF1
lipid • GH excess ... - Giantism or acromegaly ... metabolic abn #GrowthHormone ... endocrinology #pathophysiology ... #pituitary
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook 

Clinical Presentation: 
 • Classic Acromegaly: frontal
- If GH excess ... malignancy Pathophysiology ... islet cell tumor, excess ... • Pituitary ... Endocrinology #Treatment #Pathophysiology