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hepatology algorithm pathophysiology lfts management transaminitis hepatitis injury peds abnormal abscess acidosis acromegaly aflp ammonia arterial cd4 children chronic cirrhosis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - Differential ... Diagnosis Framework ... 500-1000): • Genetic ... /Metabolic Hepatopathy ... #Diagnosis #hepatology
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... Hemolysis, NASH, Genetic ... / Metabolic. ... transaminitis #differential ... #diagnosis
Common Etiologies of Cirrhosis Inflammation - Hepatitis B (15 percent) - Hepatitis C (47 percent) - Schistosomiasis
Methotrexate Genetic ... Nonalcoholic fatty liver ... 14 percent) #Diagnosis ... #Differential # ... #Causes
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 Elevated Transaminases / Transaminitis - Differential Diagnosis • Infectious: HAV, HCV, HEV, EBV, HSV, CMV •
Diagnosis • ... Trauma: Shock liver ... • Metabolic: ... #Diagnosis #causes ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... Diagnosis and Workup ... : INR/PT, aPTT(liver ... not required in all ... #Diagnosis #Causes
Causes of Fatigue - Differential Diagnosis Algorithm Endocrine • Hypo/Hyperthyroidism • Diabetes • Pituitary Insufficiency • Adrenal
Causes of Fatigue ... - Differential ... Insufficiency Metabolic ... Renal Failure • Liver ... Neoplastic / Hematologic
Causes of Failure to Thrive - Differential Diagnosis Algorithm Adequate Calorie Consumption - Increased Losses:
Causes of Failure ... Diagnosis Algorithm ... Disease • Liver ... Utilize: • Metabolic ... Pediatrics
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
free fatty acid metabolism ... = nonspecific (nausea ... infiltration) Differential ... Diagnosis: Viral ... #Pregnancy #hepatology
Schematic representation of the major sources of ammonia production and its excretory pathway (GI = gastrointestinal,
decompensated liver ... and decreased metabolism ... myeloma, CML, AML ... Hyperammonemia #Differential ... #Diagnosis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
- Differential ... Diagnosis Algorithm ... Vascular Causes ... • Metabolic/Hereditary ... #hepatology
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