15 results
Key Characteristics of Old and New Potassium-Binding Agents

- Dr. Edgar V. Lerma https://twitter.com/edgarvlermamd

#Potassium #Binding #KBinders #Kayexelate
of Old and New Potassium-Binding ... edgarvlermamd #Potassium ... Comparison #Table #Pharmacology ... #Patiromer #HyperKalemia ... #Nephrology #Agents
Veltassa (Patiromer) 
MECHANISM: Potassium Binder 
INDICATION: Treatment of Hyperkalemia 
FORMULATION: Powder for oral suspension 
DOSING: 8.4
Veltassa (Patiromer ... ) MECHANISM: Potassium ... ) is a potassium ... ACE inhibitors, ... #Hyperkalemia #Pharmacology
Potassium Binders for Management of Hyperkalemia
 • SPS - Sodium polystyrene sulfonate
 • Patiromer (veltassa)
 •
Potassium Binders ... polystyrene sulfonate • Patiromer ... cyclosilicate #Potassium ... Hyperkalemia #treatment #pharmacology ... table #comparison #nephrology
Hypokalemia Differential Diagnosis Algorithm
Hypertensive:
 • High Al, Low R - Primary aldosteronism
 • High Al, High
Hypertensive: • High ... aldosteronism • High ... Al, High R - Secondary ... Diagnosis #Algorithm #nephrology ... #causes #low #potassium
Potassium-Binding Agents to Treat Hyperkalemia
Sodium zirconium cyclosilicate (Lokelma):
 • Mechanism: Preferentially captures K in exchange for
Potassium-Binding ... ; hypokalemia Patiromer ... patients sensitive to high ... of aspiration #Potassium ... #medications #pharmacology
Management of Pediatric Kidney Stones
Acute Managment:
 • Pain relief: NSAIDs, opioids
 • Facilitating passage of stone:
Recurrence: • For ALL ... patients - High ... alkalinisation: potassium ... alkalinization: potassium ... Management #Pediatrics #nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
the basis of the potassium-to-creatinine ... mmol creatinine) High ... Urine Cl - Loop ... hypokalemia #urine #potassium ... algorithm #diagnosis #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • NSAIDs • ACE ... • Recent IV potassium ... diagnosis #causes #potassium ... #high #nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
to diarrhea, a high ... Urine chloride is high ... metabolic acidosis, a high ... of sodium and potassium ... urine #Algorithm #nephrology
Hyperkalemia - Differential Diagnosis Framework

PseudoHyperkalemia:
 • Lab error
 • Traumatic venipuncture
 • Hemolysis, thrombocytosis, leukocytosis
 •
phlebotomy High ... • NSAIDs • ACE ... • Recent IV potassium ... diagnosis #causes #potassium ... #high #nephrology