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diagnosis management treatment betadglucan causes galactomannan latenttb night sweats tb tuberculosis antibiotic aspergillus biomarkers comparison failure falsepositives laboratory nightsweats pulmonary
Causes of Antibiotic Failure - Differential Diagnosis Framework Diagnosis: • Non-Infectious: Malignant, Autoimmune, Drug-related (NMS, serotonin syndrome,
Antibiotic Failure - Differential ... bacteria: Viral, Fungal ... Source control (abscess ... ocular), Tissue activity ... (daptomycin in lungs
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
Lung Abscess - Diagnosis ... polymicrobial infection ... Lung Abscess - Clinical ... Prevotella • Fungal ... Abscess Differential
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... (NTM) • Fungal ... abscess Primary ... • Progressive lung ... characteristic features Clinical
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
affecting the lungs ... (NTM) • Fungal ... abscess Primary ... • Progressive lung ... characteristic features Clinical
Causes of Night Sweats - Differential Diagnosis • Malignancy: Lymphoma, Leukemia, Other neoplasm • Infections: Human
Night Sweats - Differential ... mononucleosis, Fungal ... coccidioidomycosis), Lung ... abscess, Endocarditis ... Autonomic over-activity
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... cut-offs defined in clinical ... surfaces - Infections ... BAL GM does not differentiate ... admin of mold-active
Night Sweats - Differential Diagnosis Framework Night sweats are a nonspecific symptom that patients commonly experience and
Night Sweats - Differential ... mononucleosis • Fungal ... coccidioidomycosis) • Lung ... abscess • Endocarditis ... Autonomic over-activity
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
surfaces, Albumin, Infections ... >90% (In most clinical ... in BAL does not differentiate ... concurrent admin mold-active ... result in + as long
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