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diagnosis betadglucan galactomannan infectiousdiseases abscess aspergillus biomarkers comparison falsepositives laboratory management pulmonary sensitivity testing treatment
Differential Diagnosis for Concurrent Brain and Lung Infections • Bacteria: Strep anginosus, Staph aureus, Klebsiella pneumoniae
Brain and Lung Infections ... Toxoplasmosis • Fungi ... #Lung #Infections ... #Concurrent #Differential ... #Diagnosis #causes
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... #Lung #Infections ... #Concurrent #Differential ... #Diagnosis #causes
Concurrent Brain and Lung Lesions • Bacteria: Nocardia spp, Strep anginosus, Staph aureus, Klebsiella pneumoniae (hypervirulent),
Concurrent Brain ... ) • Fungi: Aspergillus ... #Lung #Infections ... #Concurrent #Differential ... #Diagnosis #causes
Fungal Biomarkers: Beta-D-Glucan and Aspergillus Galactomannan Beta-D-Glucan: • Polysaccharide cell wall component of many fungi • Pathogens:
infection (IFI) ... cut-offs defined in clinical ... surfaces - Infections ... BAL GM does not differentiate ... decreased with: concurrent
Lung Abscess - Diagnosis and Management Summary Lung Abscess Etiology: • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Lung Abscess - Clinical ... Prevotella • Fungal ... #causes #management
1,3-Beta-D-Glucan and Galactomannan Testing Sensitivity Specificity and False Positives 1,3-Beta-D-Glucan • Cell wall component of many fungi
surfaces, Albumin, Infections ... >90% (In most clinical ... in BAL does not differentiate ... Sensitivity ↓ w/concurrent ... result in + as long
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