24 results
Hypernatremia Diagnosis and Workup

Step 1 . Repeat the sodium concentration.
Step 2.  Check plasma osmolality.
NORMAL PLASMA
Hypernatremia Diagnosis ... 1 . ... Repeat the sodium ... EUVOLEMIC • SIADH ... #Diagnosis #Workup
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Diagnosis Algorithm ... water retention 1) ... Low Uric Acid → SIADH ... #nephrology #sodium
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Pathophysiology 1) ... Neurological event 2) Sodium ... Pathophysiology #diagnosis ... #nephrology #hyponatremia ... #comparison
Hypernatremia Differential Diagnosis Algorithm - Diabetes Insipidus Workup

Step #1 - Consider the history
Step #2 - Assess
Hypernatremia Differential ... Diagnosis Algorithm ... Diabetes Insipidus Workup ... Step #1 - Consider ... #nephrology #insipidus
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
Modified Hyponatremia ... ON (UNa < 30): Hypovolemia ... OFF (UNa > 30): SIADH ... #Algorithm #diagnosis ... #sodium #nephrology
Hypernatremia - Differential Diagnosis Workup Algorithm

1) Check Urine Osmolality:
 > 600 mOsm/kg - Implies extrarenal mechanism
Differential Diagnosis ... 1) Check Urine ... Diagnosis #Workup ... #Algorithm #nephrology ... #sodium
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Hyponatremia Diagnosis ... EABV) - Consider: Hypovolemia ... Inappropriate - Consider: SIADH ... #diagnosis #differential ... algorithm #causes #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
+K / serum Na >1 ... Present (Uosm ≥100): Hypovolemia ... #differential # ... diagnosis #table ... #sodium #nephrology
Cancer agents and Electrolyte Disorders
 • Hypocalcemia: Cisplatin from Low Mg, Cetuximab- due to low Mg
Axitinib,
Disorders • Hypocalcemia ... Trastuzumab • Hyponatremia ... resistance, PD-1 ... #chemotherapy #diagnosis ... #differential
Hyponatremia Differential Diagnosis Table

 • Step 1: Correct for hyperglycemia. Corrected Na = [(glucose - 100)/
Hyponatremia Differential ... Diagnosis Table ... • Step 1: Correct ... #Differential # ... #nephrology #sodium