11 results
Hyponatremia Differential Diagnosis Algorithm - Utilizing Uric Acid 
ADH promotes Urea/uric acid excretion along with water
Hyponatremia Differential ... Utilizing Uric Acid ADH ... Low Uric Acid → SIADH ... #Differential # ... Diagnosis #Algorithm #nephrology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... Hypovolaemia → ADH ... Pathophysiology #diagnosis #nephrology ... #hyponatremia # ... comparison
Modified Hyponatremia Algorithm
Hypertonic Hyponatremia: Hyperglycemia, Mannitol, Urologic irrigants
Hypotonic Hyponatremia: 
 • ADH ON (UOsm > 100):
: • ADH ON (UOsm ... ON (UNa < 30): Hypovolemia ... OFF (UNa > 30): SIADH ... Algorithm #diagnosis #sodium ... #nephrology
Physiologic Approach to Hypotonic Hyponatremia
The next time you have a case of hypotonic hyponatremia, give the
restriction alone in SIADH ... , Renal Sodium loss ... Present (Uosm ≥100): Hypovolemia ... #differential # ... #nephrology
Hyponatremia - Differential Diagnosis Algorithm
Hypovolemic - Give volume
Hypervolemic (Edematous) - Look for and treat underlying cause
Hyponatremia - Differential ... • UOsm > 300 - ADH ... , SSRIs) - SIADH ... Algorithm #diagnosis #nephrology ... #sodium
Hyponatremia Diagnosis Algorithm
UOsm ≥ POsm - Vasopressin-Dependent
 • UNa < 20 mEq/L - Appropriate (↓ EABV)
Appropriate (↓ EABV ... ) - Consider: Hypovolemia ... Inappropriate - Consider: SIADH ... #diagnosis #differential ... algorithm #causes #nephrology
Hyponatremia (<135 mEq/L) is a common electrolyte abnormality caused by an excess of total body water
body water in comparison ... #hyponatremia #ADH ... #RAAS #Hypovolemia ... #EBV #potomania ... #SIADH #Thiazides
Hyponatremia - Diagnosis and Treatment
Hyponatremia is usually caused by the inability to excrete water normally.
majority of cases, ADH ... 3 questions to work ... volume status (EABV ... Treatment #management #nephrology ... #sodium
Hyponatremia - Differential Algorithm
Isotonic Hyponatremia: Hyperlipidemia, Hyperproteinemia, Recent TURP
Hypotonic Hyponatremia: 
 • Hypovolemia: Diuretics/Nephropathies, Vomiting, Diarrhea,
Hyponatremia - Differential ... : • Hypovolemia ... • Euvolemia: SIADH ... diagnosis #causes #nephrology ... #sodium #low
Primary Polydipsia
Definition: Excessive volitional water intake
Epidemiology:
 • 6-20% of patients with psychiatric disorders - Most commonly
diabetes insipidus Differential ... Pseudohyponatremia, SIADH ... intoxication Initial Workup ... , Urine Sodium ... diagnosis #management #nephrology