18 results
Major Chemotherapy Toxicities - AntiNEOPlastic Man Mnemonic

Common Toxicities with Traditional Chemotherapeutic Medications 

Originally posted on pharmacologyweekly
Major Chemotherapy ... longer active) #Chemotherapy ... #Toxicity #Toxicities ... SideEffects #Adverse #Pharmacology ... AntiNeoplastic #Man #Oncology
Chemotherapy Toxicity Bear Mnemonic - Cumulatively Toxic Drugs and their Rescues
 • Asparagine: neurotoxicity
 • Cisplatin:
Chemotherapy Toxicity ... MD @srrezaie #Chemotherapy ... #Toxicity #Bear ... Mnemonic #Drugs #pharmacology ... #oncology #SideEffects
Treatment of breast cancer: a simplified view
surgical therapy - 5-7 weeks
 - lumpectomy +
 - radiation
Treatment of breast ... mastectomy systemic chemotherapy ... adjuvant (in select cases ... breast #cancer #treatment ... timeline #simplified #oncology
Testicular Cancer - Treatment Related Toxicities

Bleomycin, Cisplatin, Etoposide, lfosfamide
Tinnitus & Hearing Loss
Neurotoxicity
Pulmonary Fibrosis
Hypotension
Nephrotoxicity
Skin Hyperpigmentation
Hemorrhagic Cystitis
Myelosuppression
Peripheral Neuropathy

Ashley
Testicular Cancer - Treatment ... Testicular #Cancer #chemotherapy ... #toxicity #toxicology ... #Toxicities #pharmacology ... #oncology
Immune Checkpoint Inhibitor Toxicity

Main Toxicities: Colitis,  
Pneumonitis, Skin adverse events, Endocrine dysfunction, 
Hepatitis,  
Myocarditis,
Checkpoint Inhibitor Toxicity ... Complications and Treatment ... CheckpointInhibitor #Toxicity ... Table #Diagnosis #Pharmacology ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
interactions) Cancer-treatment ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... Interactions #Table #Pharmacology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Toxic injury to BM ... and petechiae Causes ... Cytotoxic drugs/Chemotherapy ... aplastic anemia Treatment ... Aplastic #Anemia #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
biologics (CMV +++, EBV ... Drugs, Unknown cause ... Treatment: • ... Anti-infectious, chemotherapy ... diagnosis #management #treatment
Hydroxychloroquine is an antimalarial & DMARD (disease modifying antirheumatic drug). It is currently being discussed as
prophylaxis and treatment ... tinnitus) and may cause ... It also can cause ... (increased BB toxicity ... Hydroxychloroquine #HCQ #Pharmacology
Clozapine Toxicology
Clozapine is an atypical antipsychotic most often reserved for use in patients who have treatment-resistant
patients who have treatment-resistant ... Clozapine is known to cause ... #Toxicology #Toxicity ... #Diagnosis #Pharmacology